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Sample StackDNA Report

Generated for: Example User • January 2026

Executive Summary

Analysis of 54 genetic markers across 10 categories reveals several actionable findings that inform your supplement protocol:

  • Moderate MTHFR C677T heterozygous — reduced folate enzyme activity (~65%). Use methylfolate instead of folic acid.
  • Moderate COMT Val158Met (Met/Met) — slow dopamine clearance. Start methylation support at low doses.
  • Normal APOE ε3/ε3 — standard cardiovascular and Alzheimer’s risk profile.
  • Flagged CYP1A2 slow metabolizer — caffeine sensitivity. Limit to 1 cup/day before noon.

Methylation Pathway

Gene SNP Your Result Impact
MTHFRrs1801133AGModerate
MTHFRrs1801131TTNormal
MTRrs1805087AANormal
MTRRrs1801394AGModerate
COMTrs4680AAModerate

Your MTHFR variant reduces enzyme function by approximately 35%. Combined with your MTRR variant, methylation support with methylfolate (400–800 mcg) and methylcobalamin B12 is recommended.

Supplement Schedule Preview

Morning (with breakfast)

  • Methylfolate 400 mcg
  • Methylcobalamin B12 1000 mcg
  • Vitamin D3 + K2 (5000 IU / 100 mcg)
  • Omega-3 (EPA/DHA 1000 mg)

Evening (with dinner)

  • CoQ10 Ubiquinol 200 mg
  • Magnesium Glycinate 300 mg
  • Taurine 1000 mg

Diet & Nutrition Guidance

Based on your BCMO1 and FUT2 variants, you may benefit from preformed vitamin A sources and adjusted B12 intake strategies...

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